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Antibiotic use linked to Parkinson’s disease

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Antibiotic use linked to Parkinson’s

A higher exposure to common oral antibiotics was linked to a higher risk of Parkinson’s disease some 15 years later, according to research from Helsinki University Hospital.

The link was strongest with broad spectrum antibiotics and those that attack yeasts, fungi and anaerobic bacteria. And the disease seemed to appear 10-15 years after the damage caused.  Dr. Filip Scheperjans of the Department of Neurology said that there was increasing evidence that Parkinson’s disease originated in the gut, and this research seemed to confirm that microbial changes due to antibiotics could well play a part in the development of the disease. Inflammatory Bowel Disease, Irritable Bowel Syndrome and Constipation have been linked to an increased risk of developing Parkinson’s disease.

The study was case controlled and looked at the period 1998 – 2014. 13,976 Parkinson’s patients were compared with 40,697 non-infected persons, matched for sex, age and location. Antibiotic use was measured over three different periods – 1 to 5 years, 6-10 years and 11 to 15 years.

Go to: Neurological diseases link to lowered Butyrate-producing bacteria

Reference

  1. University of Helsinki, Health News, 22.11.2019